High-Fat Meals Linked To Fatty Liver Disease
September 5th 2008 08:39
Physicians have known for a long time that fatty liver disease can be related to alcohol consumption, diabetes and obesity, or the presence of hepatitis C virus infection. Another recently published study suggests that consuming high concentrations of fat and highly processed foods may be damaging to the liver even in the short term.
Swedish researchers subjected 18 volunteers to a four-week diet that includes two fast food meals a day and the adoption of a sedentary lifestyle aimed to increase their body weight and to determine the effect of high-calorie consumption on liver enzymes.
The study was successful in it’s purposes. Findings showed 17 of the 18 participants experienced a 5% to 15% increase in weight. The mean increase in weight was from 67.6 kg (149 lb) to 74 kg (163 lb). Thirteen participants developed pathologic alanine aminotransferase (ALT) levels in liver function. Elevated ALT levels were apparent after only one week.
According to an analysis of the third National Health and Nutrition Examination Survey, the prevalence of elevated levels of ALT or aspartate aminotransferase (AST) appears to be on the rise, as high as 7.9 percent in the US population in both men and women. Elevated ALT levels, according to the analysis, are strongly associated with features of metabolic syndrome. It may indicate that the liver is actively undergoing some sort of injury.
Swedish researchers subjected 18 volunteers to a four-week diet that includes two fast food meals a day and the adoption of a sedentary lifestyle aimed to increase their body weight and to determine the effect of high-calorie consumption on liver enzymes.
The study was successful in it’s purposes. Findings showed 17 of the 18 participants experienced a 5% to 15% increase in weight. The mean increase in weight was from 67.6 kg (149 lb) to 74 kg (163 lb). Thirteen participants developed pathologic alanine aminotransferase (ALT) levels in liver function. Elevated ALT levels were apparent after only one week.
According to an analysis of the third National Health and Nutrition Examination Survey, the prevalence of elevated levels of ALT or aspartate aminotransferase (AST) appears to be on the rise, as high as 7.9 percent in the US population in both men and women. Elevated ALT levels, according to the analysis, are strongly associated with features of metabolic syndrome. It may indicate that the liver is actively undergoing some sort of injury.
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